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生物物理及结构生物学系

王晨轩


简介
        王晨轩,1986年2月生于北京。2018年7月至今,中国医学科学院基础医学研究所/北京协和医学院基础学院生物物理与结构生物学系课题组长,专业物理化学与生物物理。
        
进入基础所工作前,研究扫描隧道显微术与原子力探针显微术的应用;纳米尺度上物质表面的物理和化学现象;淀粉样蛋白的组装结构及其调控的单分子水平研究。
        
建立课题组后的研究方向是:应用纳米技术设计抗耐药性细菌、真菌的多肽自组装材料;应用界面物理研究手段理解多肽自组装材料的抗菌机制。

联系方式
        
北京市东城区东单三条5号,老科研楼 461,邮编 100005
        
Email: wangcx@ibms.pumc.edu.cn

代表性论文

Chenxuan Wang*, C. Derek Ma, Hongseung Yeon, Xiaoguang Wang, Samuel H. Gellman#, Nicholas L. Abbott#, “Nonadditive interactions mediated by water at chemically heterogeneous surfaces: non-ionic polar groups and hydrophobic interactions”, J. Am. Chem. Soc., 2017, 139, 18536–18544.

 

C. Derek Ma*, Chenxuan Wang, Claribel Acevedo-Vélez, Samuel H. Gellman#, Nicholas L. Abbott#, “Modulation of hydrophobic interactions by proximally immobilized ions”, Nature, 2015, 517, 347-350.

 

Yanmei Wang*, Chenxuan Wang*, Zhiqiang Cheng, Dongdong Zhang, Shaopeng Li, Lusheng Song, Wenfei Zhou, Mo Yang, Zhiyou Wang, Zheng Zheng, Baohang Han, Chen Wang#, Yanlian Yang#, Jinsong Zhu#, “SPRi determination of inter-peptide interaction by using 3D supramolecular co-assembly polyrotaxane film”, Biosens. Bioelectron., 2015, 66, 38-44.

 

Chenxuan Wang*, Aihua Yang, Xia Li, Denghua Li, Min Zhang, Huiwen Du, Chao Li, Yuanyuan Guo, Xiaobo Mao, Mingdong Dong, Flemming Besenbacher, Yanlian Yang#, Chen Wang#, “Observation of molecular inhibition and binding structures of amyloid peptides”, Nanoscale, 2012, 4, 1895-1909.

 

Xiaobo Mao*, Chenxuan Wang*, Xingkui Wu, Lei Liu, Lan Zhang, Lin Niu, Yanlian Yang#, Chen Wang#, “Beta structure motifs of islet amyloid polypeptides identified through surface-mediated assemblies”, Proc. Natl. Acad. Sci. USA, 2011, 108, 19605-19610.

 

Chenxuan Wang*, Xiaobo Mao*, Aihua Yang, Lin Niu, Shengnan Wang, Denghua Li, Yuanyuan Guo, Yibin Wang, Yanlian Yang#, Chen Wang#, “Determination of relative binding affinities of labeling molecules with amino acids by using scanning tunneling microscopy”, Chem. Commun., 2011, 47, 10638-10640.