The Center for Proteomics of Chinese Academy of Medical Sciences was founded in 2002, under the auspices of Chinese Academy of Medical Sciences. With major financial support from Ministry of Science and Technology, the center acquired state-of the-art instrumentation such as LCQ XP+ electrospray ion trap mass spectrometer and Voyager matrix-assisted laser desorption time-of-flight mass spectrometer for protein identification, as well as 2-dimentional electrophoresis systems and 2-dimentional liquid chromatography systems for protein isolation. Research projects undertaken in the Center for Proteomics include clinical cancer biomarker identification, the first-in-the-world profiling of normal human urinary proteome and glycoproteome, and development of novel bioinformatic techniques such as AMASS. Papers are published in major proteomic journals such as Molecular & Cellular Proteomics and Proteomics. In addition, the center also provides proteomic services for dozens of research institutes and biotech companies.

In 2007, to better advance the mission of the center, it moved to the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and began providing integrated proteomics research services, serving as a part of Core Laboratories Center. To keep in pace with the rapid development in the field, the center made significant investment in equipment upgrades and new technology development in the past three years. Current instrument in operation include Orbitrap Fusion Lumos Tribrid and LTQ Orbitrap Velos from Thermo Fisher, Triple 5600 and QTRAP6500 from AB sciex, UltraflexExtreme MALDI-TOF/TOF from Bruker, Quattro Micro from Waters. The proteomics services provided by the center include peptide and protein analysis and identification, accurate molecular weight analysis, posttranslational modification characterization, differential proteome analysis, metabolites analysis and identification and differential metabolomics analysis. The center strives to provide a full range of quality proteomics and metabolomics service to the research community.

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