Immunotherapy Center of Chinese Academy of Medical Sciences (IC, CAMS) was established in April, 2015, IBMS/CAMS. It consists of three research units, including Department of Immunology at IBMS, Department of Immunology at Cancer Hospital, and Institute of Medical Biology within CAMS. The IC focuses on vaccine design, adoptive cellular immunotherapy, antibody development, and preparation of recombinant proteins in the control of cancer, infection diseases and autoimmune diseases. The goal of IC is to establish an integrated immunotherapy platform for prevention and treatment of “chronic diseases”, and performing innovative research about pathological mechanism and immunotherapeutics of immune disorders, and strengthening the translation of basic research to clinical practice as well.
The ongoing research projects include antibody development, tumor adoptive cellular immunotherapeutic technology, and investigation of mechanism of innate immunity and tumor immunity. For example, we have obtained potent neutralizing antibodies against ARTN and also established the optimization of activated GFRa3 and clec12A-CAR T cells. Besides, a novel of biological and potential clinical significance of glucose metabolism in tumor-promoting TAMs was discovered and reported. In 2022, several original papers and reviews were published in Cancer Cell, Signal Transduction and Target Therapy, Journal of Autoimmunityand so on.
Members of Academic Committee:
Director: Prof. Zhigang Tian, School of Life Sciences, University of Science and Technology of China.
Deputy Director: Prof. Xue Zhang, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences.
Other Members:
Prof. Bo Huang, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences
Prof. Changyou Wu, Institute of Immunology, Zhongshan School of Medicine
Prof. Xiaoning Wang, The General Hospital of the People's Liberation Army
Prof. Tao Wan, The Second Military Medical University
Prof. Jiyan Zhang, Department of Immunology, Academy of Military Medical Sciences
Director: Dr. Xuetao Cao
Deputy Directors: Dr. Wei He, Dr. Shuren Zhang, Dr. Qihan Li