"张祝琴，男，中国医学科学院基础医学研究所生化系刘德培课题组副研究员。北京大学医学部预防医学专业本科毕业，北京协和医学院基础学院生化与分子生物学博士。 从事基因表达调控与基因治疗研究。发现肝脏转录因子HNF4alpha可以调节ACAT2的调节，并发现两个新的调节位点（ActaBiochimBiophys Sin，2012），发现饱和脂肪酸促进ACAT2的表达（Chin Med Sci J 2010）,发现表观遗传修饰酶Sirt6影响免疫分子NKG2D的配体表达并影响动脉粥样硬化的发生（Sci Rep 2016）,而Sirt1影响巨噬细胞极化并进而影响主动脉瘤发生（J Genet Genomics）。发现Sirt6通过增加Nrf2的稳定性增强抗氧化应激能力（Exp Cell Res，2023）。参与发表多篇文章，阐述Sirt1对于代谢和炎症基因的调节作用。参与发表综述对中国大陆的病毒基因治疗进行总结。 "

Liu XZ, Ren SC, Li ZZ, Hao DL, Zhao X, Zhang ZQ#, Liu DP#. Sirt6 mediates antioxidative functions by increasing Nrf2 abundance. Exp Cell Res, 2023. 422(1): 113409.

Zhang ZQ*, Xu J*, Liu Y, Wang TT, Pei JF, Cheng LQ, Hao DL, Zhao X, Chen HZ, Liu DP. Mouse macrophage specific knockout of SIRT1 influences macrophage polarizationand promotes angiotensin II-induced abdominal aortic aneurysm formation. J Genet Genomics. 2018 Jan 20;45(1):25-32.

Zhang ZQ*, Ren SC*, Tan Y*, Li ZZ, Tang XQ, Wang TT, Hao DL, Zhao X, Chen HZ, Liu DP. Epigenetic regulation of NKG2D ligands is involved in exacerbated atherosclerosis development in Sirt6 heterozygous mice. Sci Rep 2016;6:23912.(*co-first author)

Zhang ZQ, Liu JJ, Xi Y, Yang RF, Chen HZ, Li ZY, Liu DP, Liang CC. Two novel cis-elements involved in hepatocyte nuclear factor 4alpha regulation of acyl-coenzyme A:cholesterolacyltransferase 2 expression. ActaBiochimBiophys Sin (Shanghai) 2012;44(2):162-71.

Zhang ZQ, Chen HZ, Yang RF, Zhang R, Jia YY, Xi Y, Liu DP, Liang CC.Regulation of acyl-coenzyme A: cholesterol acyltransferase 2 expression by saturated fatty acids. Chin Med Sci J 2010;25(4):222-7.

Zhang ZQ, Chen HZ, Liu DP. Translational research: lessons from past research, growing up nowadays, and development goal in future. Sci China Life Sci 2011;54(12):1085-8.

Chen HZ, Zhang ZQ, Wei YS, Liu DP. [Research progression of deacetylase (Sirt1)]. Zhongguo Yi XueKeXue Yuan XueBao 2007;29(3):441-7.

Lin Q, Wang DG, Zhang ZQ, Liu DP. Applications of Virus Vector-Mediated GeneTherapy in China. Hum Gene Ther. 2018 Feb;29(2):98-109.