"研究红系造血分化发育，包括 1.正常红系造血和贫血性疾病的遗传、表观遗传和3D基因组调控；2.红细胞脱核的分子细胞生物学机制；3. 贫血发病机制和治疗。主要研究工作发表在Blood、Redox Biol、 Nucleic Acids Res (2012, 2016)、 Mol Cell Biol、 J Biol Chem、J Genet Genomics、 FASEB J 等杂志。"

1. Xinjun Hu*, Jiaxin Wang*, Ke Yang*, Hong Fan*, Jie Wu*, Jiuqiang Ren, Gaijing Han, Jing Li, Zheng Xue, Xuehui Liu#, Xiang Lv#. The GWAS SNP rs80207740 modulates erythrocyte traits via allele-specific binding of IKZF1 and targeting XPO7 gene. FASEB J, 2024, 38(10): e23666.

2. Ke Yang*#, Tianqi Zhu*, Jiaying Yin*, Qiaoli Zhang, Jing Li, Gaijing Han, Weiyin Xu, Nan Liu#, Xiang Lv#. The non-canonical poly(A) polymerase FAM46C promotes erythropoiesis. J Genet Genomics. 2024 Feb 24:S1673-8527(24)00032-8.

3. Gaijing Han*, Cong Cao*, Xi Yang*, Guo-Wei Zhao*, Xin-Jun Hu, Dong-Lin Yu, Rui-Feng Yang, Ke Yang, Ying-Ying Zhang, Wen-Tian Wang, Xiu-Zhen Liu, Peng Xu, Xue-Hui Liu, Ping Chen, Zheng Xue#, De-Pei Liu#, Xiang Lv#. Nrf2 expands the intracellular pool of the chaperone AHSP in a cellular model of β-thalassemia. Redox Biol. 2022, 50:102239.

4. Guo-You Liu*, Guang-Nian Zhao*, Xiao-Feng Chen, De-Long Hao, Xiang Zhao, Xiang Lv#, De-pei Liu#. The long noncoding RNA Gm15055 represses Hoxa gene expression by recruiting PRC2 to the gene cluster. Nucleic Acids Res, 2016, 44(6):2613-27.

5. Jie Wu*, Li-Quan Zhou*, Wei Yu*, Zhi-Guo Zhao, Xue-Min Xie, Wen-Tian Wang, Jian Xiong, Man Li, Zheng Xue, Xing Wang, Peng Zhang, Bei-Bei Mao, De-Long Hao, Xiang Lv#, De-Pei Liu1#. PML4 facilitates erythroid differentiation by enhancing the transcriptional activity of GATA-1. Blood, 2014, 123(2):261-70.

6. Li-Quan Zhou*, Jie Wu*, , Wen-Tian Wang, Guang-Nian Zhao, Wei Yu, Peng Zhang, Jian Xiong, Man Li, Zheng Xue, Xing Wang, Zhi-Chen Guo, Xiang Lv#, De-Pei Liu#. SATB2 Promotes Expression and Physical Association of Human GGamma- and AGamma-Globin Genes. J Biol Chem 2012, 287(36):30641-52.

(* Co-first authors, # Co-corresponding authors)