林骏，助理教授/研究员，博士研究生导师。代谢性疾病分子机制研究课题组组长，中国生物物理学会肠道菌群分会委员。 院校引进人才，2026年加入院校，曾于2024-2026年在首都医科大学附属北京朝阳医院任助理研究员，于2021-2023年北京大学从事博士后研究。博士毕业于中国科学学院大学（培养单位中国科学院动物研究所）。

长期聚焦代谢性疾病发生发展过程中内源性物质的作用以及其宿主靶点的解析：阐明了菌源新胆酸改善代谢性疾病的作用，发现菌源新胆酸的全新受体以及改善葡萄糖耐量的分子机制；揭示了神经酰胺抑制脂肪棕色化及产热的关键受体。以第一（含共同）作者在 Cell、 Science、 Cell Metab.、Adv. Sci.、 PNAS等国际知名刊物发表 SCI 论文 12 篇，研究工作获得2025 年度中国生命科学十大进展。

1. Lin J#, Nie Q#, Cheng J#, Zhong Y#, Zhang T#, Zhang X#, Ge X#, Ding Y#, Niu C, Gao Y, Wang K, Gao M, Wang X, Chen W, Yun C, Ye C, Xu J, Shaoyong W, Zhang L, Shang P, Luo X, Zhang Z, Zheng X, Sha X, Zhang J, Nie S, Zhang X, Ren F, Liu H, Dong E, Yu X*, Ji L*, Pang Y*, Sun J*, Jiang C*. A microbial amino acid-conjugated bile acid tryptophan-cholic acid improves glucose homeostasis via the orphan receptor MRGPRE. Cell. 2025 August;188, 1-19

2. Lin H#, Ma C#, Cai K#, Guo L#, Wang X#, Lv L#, Zhang C#, Lin J#, Zhang D, Ye C, Wang T, Huang S, Han J, Zhang Z, Gao J, Zhang M, Pu Z, Li F, Guo Y, Zhou X, Qin C, Yi F, Yu X*, Kong W*, Jiang C*, Sun JP*. Metabolic signaling of ceramides through the FPR2 receptor inhibits adipocyte thermogenesis. Science. 2025 May;388(6746)

3. Ye C#, Wang X#, Lin J#, Wu C, Gao Y, Guo C, Liao Y, Rao Z, Huang S, Chen W, Huang Y, Sun J, Zhao D*, Jiang C*. Systematical identification of regulatory GPCRs by single-cell trajectory inference reveals the role of ADGRD1 and GPR39 in adipogenesis.  Sci China Life Sci. 2025 Apr;68(4)

4. Lin J, Liu H, Sun Y, Zou J, Nie Q*, Nie S*. Arabinoxylan Alleviates Obesity by Regulating Gut Microbiota and Bile Acid Metabolism. J Agric Food Chem. 2024 Oct 23;72(42).

5. Zhang Y#, Wang X#, Lin J#, Liu J#, Wang K, Nie Q, Ye C, Sun L, Ma Y, Qu R, Mao Y, Zhang X, Lu H, Xia P, Zhao D, Wang G*, Zhang Z*, Fu W*, Jiang C*, Pang Y*. A microbial metabolite inhibits the HIF-2α-ceramide pathway to mediate the beneficial effects of time-restricted feeding on MASH. Cell metabolism. 2024 Aug 6;36(8)

6. Yan C#, Lin J#, Huang Y#, Gao Q#, Piao Z#, Yuan S, Chen L, Ren X, Ye R, Dong M, Zhang H, Zhou H, Jiang X, Jin W*, Zhou X*, Yan C*. Population genomics reveals that natural variation in PRDM16 contributes to cold tolerance in domestic cattle. Zoological research. 2022 Mar 18;43(2):275-284.

7. Jiang X#, Lin J#, Dong M, Liu X, Huang Y, Zhang H, Ye R, Zhou H, Yan C, Yuan S, Chen L, Jiang R, Zheng K, Jin W*. Overexpression of Pregnancy Zone Protein in Fat Antagonizes Diet-Induced Obesity Under an Intermittent Fasting Regime. Frontiers In Physiology. 2022 Aug 16;13:950619.

8. Lin J#, Jiang X#, Dong M, Liu X, Shen Q, Huang Y, Zhang H, Ye R, Zhou H, Yan C, Yuan S, Wu X, Chen L, Wang Y, He M, Tao Y, Zhang Z*, Jin W*. Hepatokine Pregnancy Zone Protein Governs the Diet-Induced Thermogenesis Through Activating Brown Adipose Tissue. Advanced science. 2021 Nov;8(21).

9. Zheng Q#, Lin J#, Huang J#, Zhang H, Zhang R, Zhang X, Cao C, Hambly C, Qin G, Yao J, Song R, Jia Q, Wang X, Li Y, Zhang N, Piao Z, Ye R, Speakman JR, Wang H, Zhou Q, Wang Y*, Jin W*, Zhao J*. Reconstitution of UCP1 using CRISPR/Cas9 in the white adipose tissue of pigs decreases fat deposition and improves thermogenic capacity. Proc Natl Acad Sci USA. 2017, Nov 7, 114(45): E9474-E9482

10. Lin J#, Cao C#, Tao C#, Ye R, Dong M, Zheng Q, Wang C, Jiang X, Qin G, Yan C, Li K, Speakman JR, Wang Y*, Jin W*, Zhao J*. Cold adaptation in pigs depends on UCP3 in beige adipocytes. Journal of Molecular Cell Biology. 2017, Oct 1;9(5):364-375.

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