中国医学科学院基础医学研究所(北京协和医学院基础学院)

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2025年度论文动态

3D Body Scanning-Derived Normative Values of Appendicular Circumferences: A Novel Tool for Sarcopenia Screening in Chinese Adults

2026.04.03
AhR-Siglec-15 axis regulates lysosomal Ca2+ release for sonic hedgehog medulloblastoma growth via TRPML1

2026.04.03
Heterozygous human JAK2V617F activates AhR to drive essential thrombocythemia and promote thrombosis

2026.04.03
Activation of T Cell-Intrinsic p53 by Acetylation Elicits Antitumor Immunity to Boost Cancer Immunotherapy

2026.04.03
Beyond the Amyloid Core: Modulation of Aggregate Conformational Diversity by Mutations in the Noncore Regions

2026.04.03
Molecular characterization of endosomal self RNA Rmrp-engaged TLR3 dimerization to prime innate activation

2026.04.03
Mechanical signaling via β2 integrin decouples T cell proliferation and differentiation for generating stem cell-like CAR T cells

2026.04.03
Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance

2026.04.03
Pharmacological inhibition of PSPH reduces serine levels and epileptic seizures

2026.04.03
Submolecular Resolution of β‑Sheet Plasticity: Decoding Mutations and PTMs in Protein Aggregation Disorders

2026.04.03
Glucose-1-phosphate promotes compartmentalization of glycogen with the pentose phosphate pathway in CD8+ memory T cells

2026.04.03
UFMylation safeguards human hepatocyte differentiation and liver homeostasis by regulating ribosome dissociation

2026.04.03
Oncogenic fusions converge on shared mechanisms in initiating astroblastoma

2026.04.03
The oncoprotein SET promotes serine-derived one-carbon metabolism by regulating SHMT2 enzymatic activity

2026.04.03
A dual chemodrug-loaded hyaluronan nanogel for differentiation induction therapy of refractory AML via disrupting lysosomal homeostasis

2026.04.03
Selective translational control by PABPC1 phase separation regulates blast crisis and therapy resistance in chronic myeloid leukaemia

2026.04.03
Iron-Doxorubicin Hyaluronan Nanogel as an Effective Targeted Chemotherapy with Modulated Cardiotoxicity

2026.04.03
GOLM1 Promotes Atherogenesis by Activating Macrophage EGFR-ERK Signaling Cascade

2026.04.03
Posttranscriptional Control of Neural Progenitors Temporal Dynamics During Neocortical Development by Syncrip

2026.04.03
SEE: A Method for Predicting the Dynamics of Chromatin Conformation Based on Single-Cell Gene Expression

2026.04.03

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